Level and distribution of 20-hydroxyecdysone during Pfaffia glomerata development
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چکیده
منابع مشابه
Phytochemical analysis of Pfaffia glomerata inflorescences by LC-ESI-MS/MS.
Pfaffia glomerata contains high levels of β-ecdysone, which has shown a range of beneficial pharmacological effects. The present study demonstrated that inflorescences of P. glomerata contain other important bioactive compounds in addition to β-ecdysone. The identification of compounds from inflorescences using liquid chromatography coupled with electrospray ionization tandem mass spectrometry ...
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The insect steroid hormone 20-hydroxyecdysone (20E) acts through a specific nuclear receptor complex, ecdysone receptor (EcR) and ultraspiracle (USP). EcR and USP are FXR/LXR and RXR orthologs, respectively, which play critical roles in the regulation of lipid metabolism in mammals. Lipid concentration in Bombyx hemolymph and lipase activity in fat body peaked during molting and pupation, sugge...
متن کاملMechanism of C-2 hydroxylation during the biosynthesis of 20-hydroxyecdysone in Ajuga hairy roots.
Feeding synthetic [2beta-2H]- and [2alpha-2H]-cholesterols to the hairy roots of Ajuga reptans var. atropurpurea and 2H-NMR analysis of the biosynthesized 20-hydroxyecdysone revealed that hydroxylation at C-2 proceeds with retention of configuration. Feeding [2alpha,3alpha-2H2]cholesterol followed by 2H-NMR analysis of the 2,3,22-triacetate of the resulting 20-hydroxyecdysone ruled out a mechan...
متن کاملThe role of 20-hydroxyecdysone signaling in Drosophila pupal metabolism.
In holometabolous insects, the steroid hormone 20-hydroxyecdysone (20E), in coordination with juvenile hormone, regulates the major developmental events that promote larval development and the transition from the larval to the pupal stage. Intimately entwined with the hormonal control of development is the control of larval growth and the acquisition of energy stores necessary for the developme...
متن کاملMET Is Required for the Maximal Action of 20-Hydroxyecdysone during Bombyx Metamorphosis
Little is known about how the putative juvenile hormone (JH) receptor, the bHLH-PAS transcription factor MET, is involved in 20-hydroxyecdysone (20E; the molting hormone) action. Here we report that two MET proteins found in the silkworm, Bombyx mori, participate in 20E signal transduction. Met is 20E responsive and its expression peaks during molting and pupation, when the 20E titer is high. A...
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ژورنال
عنوان ژورنال: Brazilian Journal of Plant Physiology
سال: 2008
ISSN: 1677-0420
DOI: 10.1590/s1677-04202008000400006